120: Long term engraftment after allogeneic transplantation for beta-thalassemia major
نویسندگان
چکیده
منابع مشابه
Determinants of engraftment after allogeneic marrow transplantation.
ESPITE RECENT improvements in posttransplant D immunosuppressive regimens, acute and chronic graftversus-host disease (GVHD) remain significant obstacles to successful marrow transplantation, particularly in patients not having an HLA-identical related donor. These findings have lead to continued interest in preventing GVHD by depleting T cells from the donor marrow. Initial animal experiments ...
متن کاملLong-term physiological side effects after allogeneic bone marrow transplantation.
Allogeneic bone marrow transplantation (allo-BMT) or stem cell transplantation has the potential to cure a significant proportion of patients with otherwise fatal diseases. At present, immediate survival is no longer the sole concern after allo-BMT, because many patients can survive the acute complications of the procedure and remain free of their original disease for several years. Although lo...
متن کاملMixed chimerism after bone marrow transplantation for thalassemia major.
Thirty-four thalassemia patients were studied for chimerism by fluorescent in situ hybridization or variable number tandem repeats after bone marrow transplantation. Mixed chimerism was detected in 9 patients with host cells ranging from 4 to 56%. One had graft rejection and the others were transfusion independent. Mixed chimerism was common but mostly without deleterious effect.
متن کاملEndocrine Disorders in Beta thalassemia Major Patients
Background Thalassemia is the most common hereditary disorder worldwide. The patient's’ survival is dependent on lifetime blood transfusion which leads to iron overload and its toxicity on various organs including endocrine glands. The study aimed to investigate endocrine disorders in patients with Beta-thalassemia major in the Southern Khorasan province, Iran. Materials and Methods In this des...
متن کاملLong-term remission after allogeneic hematopoietic stem cell transplantation for refractory cutaneous T-cell lymphoma.
BACKGROUND Allogeneic hematopoietic stem cell transplantation has proved to be an effective therapeutic option in various hematologic neoplastic disorders. Because patients with advanced cutaneous T-cell lymphoma have a poor prognosis, with minimal possibilities of sustained remission, we studied the therapeutic potential of hematopoietic stem cell transplantation. OBSERVATIONS Three young pa...
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ژورنال
عنوان ژورنال: Biology of Blood and Marrow Transplantation
سال: 2007
ISSN: 1083-8791
DOI: 10.1016/j.bbmt.2006.12.124